Other Rankings: QB RB WR TE
| 1 | Adrian Peterson | MIN | vs BUF |
| 2 | Arian Foster | HOU | at PHI |
| 3 | Maurice Jones-Drew | JAX | at TEN |
| 4 | Chris Johnson | TEN | vs JAX |
| 5 | Peyton Hillis | CLE | at MIA |
| 6 | LeSean McCoy | PHI | vs HOU |
| 7 | Frank Gore | SF | at GB |
| 8 | Steven Jackson | STL | at ARI |
| 9 | Jamaal Charles | KC | vs DEN |
| 10 | Michael Turner | ATL | at TB |
| 11 | Ahmad Bradshaw | NYG | vs WAS |
| 12 | Rashard Mendenhall | PIT | at BAL |
| 13 | Matt Forte | CHI | at DET |
| 14 | Ray Rice | BAL | vs PIT |
| 15 | Knowshon Moreno | DEN | at KC |
| 16 | Felix Jones | DAL | at IND |
| 17 | Fred Jackson | BUF | at MIN |
| 18 | LaDanian Tomlinson | NYJ | at NE |
| 19 | Mike Goodson | CAR | at SEA |
| 20 | Tim Hightower | ARI | vs STL |
| 21 | LeGarrette Blount | TB | vs ATL |
| 22 | Darren McFadden | OAK | at SD |
| 23 | Cedric Benson | CIN | vs NO |
| 24 | Marshawn Lynch | SEA | vs CAR |
| 25 | BenJarvus Green-Ellis | NE | vs NYJ |
| 26 | Mike Tolbert | SD | vs OAK |
| 27 | Keiland Williams | WAS | at NYG |
| 28 | Danny Woodhead | NE | vs NYJ |
| 29 | Donald Brown | IND | vs DAL |
| 30 | Reggie Bush | NO | at CIN |
| 31 | Jahvid Best | DET | vs CHI |
| 32 | Brandon Jackson | GB | vs SF |
| 33 | Shonn Greene | NYJ | at NE |
| 34 | Beanie Wells | ARI | vs STL |
| 35 | Ricky Williams | MIA | vs CLE |
